Beta-Thalassemia, Hyperlipoproteinemia(a), And Metabolic Syndrome: Its Low-Cost Holistic Therapy

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Beta-thalassemia, hyperlipoproteinemia(a), and metabolic syndrome: its low-cost holistic therapy.

Metabolic syndrome (MS) is an emerging global health problem. Although studies highlighting its genetic, lipid, and cardiometabolic associations have been described in detail, the exact cause for these associations is not clear. The authors describe, in this study, the case of a patient who, along with his family members, had clinical evidence of MS. In addition, this patient also exhibited bet...

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Visual and Auditory Complications during Deferasirox Therapy in Beta-thalassemia

Background:  Deferasirox is an oral iron chelator widely used to treat iron overload in patients with transfusion-dependent β-thalassemia. This study investigated the prevalence of visual and auditory complications caused by deferasirox. Materials and Methods: This cross-sectional study included 156 patients aged less than 18 years with transfusion-dependent β-thalassemia and deferasirox iron...

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Beta thalassemia gene therapy using lentiviral vectors

Recent years, allogeneic bone marrow transplantation (BMT) has proved to be the successful cure for patients with thalassemia major, however this is restricted due to limited matched-related donor. Its complications include chronic graft-versus-host disease in 5-8% of patients. So, a molecular approach, such as gene therapy for direct normal beta globin gene transmission, seems quite promising ...

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Prevalence of metabolic syndrome in patients with minor beta thalassemia and its related factors: a cross-sectional study

BACKGROUND Atherosclerotic disorders, hypertension and lipid profile alterations are of a lower prevalence in patients with minor beta thalassemia. On the other hand, nowadays, metabolic syndrome is considered as one of the major risk factors of developing cardiovascular diseases. Therefore, the present study was performed to determine the prevalence of metabolic syndrome in patients with minor...

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Moyamoya syndrome (MMS) is a progressive disorder. We report a 19-year-old boy with beta-thalassemia who presented with a left hemiparesis. Brain MRI showed old middle cerebral artery and left frontal subcortical white matter infarcts. Brain magnetic resonance angiography and digital subtraction angiography revealed occlusion of the bilateral internal carotid arteries with a rich network of bas...

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ژورنال

عنوان ژورنال: The Journal of Alternative and Complementary Medicine

سال: 2007

ISSN: 1075-5535,1557-7708

DOI: 10.1089/acm.2006.6359